Rseb 
v0.3.5 - January 06th 2025
- Bug fixing in the 
incucytefunction when color column is provided in the metadata. 
v0.3.4 - August 03rd 2024
- Improved the multiplot visualization of the output from 
evaluate.heterogeneityfunction. - Added possibility of sample clustering for 
evaluate.heterogeneityfunction. - Updated the dependencies to be compatible with new functions/features: patchwork, ggh4x, Hmisc.
 - Bug fixed in the 
incucytefunction. - Performance optimized for 
DE.statusfunction - Bug fixed in ggplot2 function calling in 
plot.NES - Bug fixed in 
plot.gseaandplot.multi.gsea - Bug fixed in 
volcanoto do not drop color levels - Added zenodo reference
 
v0.3.3 - January 28th 2024
- Bug fixing in 
incucytefunction - Added functions 
plot.multi.gsea,plot.NES - Solved issue for incompatibility between files with and without ‘chr’ in 
evaluate.heterogeneityfunctions - Dot strokes automatically removed in the 
volcanofunction in order to reduce the plot size for publications 
v0.3.2 - September 18th 2023
- Update of 
evaluate.heterogeneityto enable the log1p signal in the heatmap and avoid scientific annotation of the rank numbers - Minor bug-fixing in the 
evaluate.heterogeneity - Added new function 
plot.gsea - Dependencies update to include 
enrichplotandRColorBrewerrequired forplot.gsea 
v0.3.1 - December 10th 2022
- New functions added: 
evaluate.heterogeneity,incucyte,read.computeMatrix.file,intersect.regions,venn.overlapandclosest.regions - Updated the dependencies to be compatible with new functions: scales, grDevices, R.utils, eulerr, IRanges and pryr
 - Added the possibility to export a file with the session info in the function 
pkg.version - Bug fixing for abs(number) < 1 in 
floating.floorandfloating.ceiling - Optimized alignment of the plot for 
plot.density.differences,plot.density.profile,plot.density.profile.smoothandplot.density.summary 
v0.3.0 - August 15th 2022
- Improvement of 
sort.bedusage: a) removed redundant “export.bed” option (now it is sufficient to add a file name in the “export.file.name” parameter if exporting is wished), b) added the “unique.regions” option, c) minor bug fixed insort.bedfor input class check - Added option ‘verbose’ for 
sort.bedandcollapse.bedfunctions - Added citation file to cite the article associated to this package
 - Improvement of the vignette
 - Changed the default value for command string parameter for 
intersect.bedandcomputeMatrix.deeptoolsfunctions - Bug-fixing for the handling of data.frames inputs in the function 
density.matrix - Bug-fixing for the handling of bigWig inputs that do not contain ‘chr’ in the seqnames/chromosome names for the function 
density.matrix - Added stranded option in the function 
density.matrix, allowing the possibility to reverse the signal of strand ‘-‘ regions - Addition of diffloop dependence used to handle bigWig inputs that do not contain ‘chr’ in the seqnames for the function 
density.matrix - Added new function 
get.single.base.score.bw - Added new function 
plot.density.profile.smooth - Added new function 
genomic.tracks - Added new function 
qPCR.rna.exp - Added new function 
qPCR.resultsexample - Updated dependencies to satisfy 
genomic.tracksandqPCR.rna.exprequirements: colorspace, ggbio, ggforce, GenomicRanges, AnnotationFilter, EnsDb.Hsapiens.v75, EnsDb.Hsapiens.v86, EnsDb.Mmusculus.v79, openssl, readxl, jpeg 
v0.2.0 - April 13th 2021
- Updated information in DESCRIPTION file (new suggested: 
ggpmisc,prettydoc,knitr,rmarkdown,stats) - Added vignette to describe the main functions of the package
 - Added function 
density.matrix(alternative tocomputeMatrix.deeptools) - Added example datasets 
RNAseq,deeptools.matrix,CNV.table - New function 
plot.density.differences - Updtate 
actualizefunction to build vignettes and bugs fixed - Optimized the 
plot.density.summaryandplot.density.profilefunctions in order to not interfer with other packages - Optimized the 
plot.density.summaryandplot.density.profilefunctions in order to keep the input order of the samples and groups in the plots colors/legend - Updated 
plot.density.profileto change legend title when ‘plot.by.group==FALSE’ - Updated 
plot.density.summaryto compute the means comparisons even when not required to show on the plot and indicate whether the statistical test performed was paired or not - Bug fixed in matrix loading for 
plot.density.summaryfunction - Better handling of Rseb version visualization in 
pkg.versionoutput 
v0.1.7 - February 20th 2021
- Updated information in DESCRIPTION file
 - Updated the dependencies to require an R version >= 4.0.0
 - Moved all “depending” packages in “imports” to avoid attaching of all packages. Morover, added 
ggpubrand removedlabeling - Bug fixing in 
actualizeanduniform.x.axisfunctions - Optimization for better definition of the breaks in the functions 
uniform.x.axisanduniform.y.axis - Optimization of package handling for 
plot.density.summaryandplot.density.profile - Optimized color handling for summary plots in 
plot.density.summaryfunction - Now computation and plot of the statistical mean comparisons is available for 
plot.density.summary - In the 
plot.density.summaryfunction a density profile corresponding to the summary plot subset range is generated - The data.table of 
plot.density.summarynow contains also the orignal positions used to generate the matrix - Optimization of 
IGVsnapfunction and improvment of relative manual information IGVsnapallows the addiction of a delay time between snap generation
v0.1.6 - February 10th 2021
- Added the function 
actualizeand integrated in each function to check everytime ifRsebpackage is up-to-date - New functions 
plot.density.summary,floating.ceiling,floating.floor - Updated the dependencies to add 
rvcheckandcurl - Optimization for different labeling and better handle of Y-axis autoscale in 
plot.density.profilefunction - Optimization of 
uniform.x.axisanduniform.y.axiswith the new functionsfloating.ceilingandfloating.floorand to support a given number of digits 
v0.1.5 - January 29th 2021
DE.statusnow supports also NAs for the FoldChange- Added functions 
color.gradientandis.color - Bugs fixed in 
volcano 
v0.1.4 - January 15th 2021
- Bugs fixed in 
plot.density.profile - Bugs fixed in 
build.bed - Bugs fixed in 
intersect.bedtools - Updated dependencies required (
labeling) - Added functions 
uniform.x.axisanduniform.y.axis 
v0.1.3 - January 11th 2021
- Optimization of 
volcanofunction: parameter ‘font_size’ added - Bugs fixed in 
computeMatrix.deeptools - Added function 
build.bed - Added R version dependence (set to R >= 3.2.0) to be compatible with 
dplyr 
v0.1.2 - January 7th 2021
- Optimization of 
IGVsnapfunction - Added the function 
pkg.check 
v0.1.1 - January 6th 2021
- Some bug-fixing
 - Added the function 
read.computeMatrix.file - Optimized function 
plot.density.profileto be compatibile with outputs fromread.computeMatrix.file 
v0.1.0 - January 5th 2021
First release.